| Titel | Genre |
|---|---|
| Shantae: Half-Genie Hero | Action |
| Sherlock Holmes: The Devil's Daughter | Adventure |
| Shin Megami Tensei III: Nocturne | Rollenspiel / RPG |
| Shin Megami Tensei V | Rollenspiel / RPG |
| Shining Resonance Refrain | Rollenspiel / RPG |
| Sid Meier's Civilization VI | Strategie |
| Sine Mora EX | Shooter |
| Skylanders Imaginators | Action |
| Sniper Elite 4 | Shooter |
| SNK 40th Anniversary Collection | Sammlung |
| SNK Heroines: Tag Team Frenzy | Beat'em'Up |
| Sonic Mania | Jump'n'Run |
| South Park: The Fractured But Whole | Rollenspiel / RPG |
| Splatoon 2 | Shooter |
| Splatoon 3 | Shooter |
| Spy x Anya: Operation Memories | Adventure |
| Spyro Reignited Trilogy | Jump'n'Run |
| Star Ocean: First Departure R | Rollenspiel / RPG |
| Star Ocean: The Second Story R | Rollenspiel / RPG |
| Stardew Valley | Simulation |
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